Description

1-(Bromomethyl)-2-Cyclopropylbenzene is a versatile brominated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its reactive benzylic bromide moiety, which facilitates efficient carbon-carbon and carbon-heteroatom bond formation. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing cyclopropyl and substituted benzyl motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where the cyclopropylbenzene scaffold is pharmacologically relevant.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine or nitrogen-based ligands for transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or advanced polymers with tailored properties.
• Cross-Coupling Reactions: An effective electrophile in Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Substitution: The benzylic bromide is highly reactive towards various nucleophiles, enabling the introduction of diverse functional groups.

Basic Information

Product Name	1-(Bromomethyl)-2-Cyclopropylbenzene
CAS No.	1260801-90-8
Molecular Formula	C10H11Br
Molecular Weight	211.10 g/mol
Synonyms	2-Cyclopropylbenzyl Bromide; (2-Cyclopropylphenyl)methyl Bromide; α-Bromo-2-cyclopropyltoluene; o-Cyclopropylbenzyl Bromide; 1-Bromomethyl-2-cyclopropylbenzene; 2-(Bromomethyl)cyclopropylbenzene; Bromomethyl Cyclopropylbenzene
EINECS	Contact for details

Quality Control

Our production of 1-(Bromomethyl)-2-Cyclopropylbenzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.