Description

1-Chloroisoquinolin-4-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for the development of novel pharmacologically active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new libraries of nitrogen-containing heterocycles for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the creation of novel active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for the synthesis of specialized organic ligands and functionalized polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	1-Chloroisoquinolin-4-Amine
CAS No.	1260799-38-9
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	4-Amino-1-chloroisoquinoline; 1-Chloro-4-aminoisoquinoline; 1-Chloro-4-isoquinolinamine; 4-Isoquinolinamine, 1-chloro-; 1-Chloroisoquinoline-4-amine; 1260799-38-9; 4-Amino-1-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinolin-4-Amine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.