Description

1-Chloroisoquinoline-4-Carboxylic Acid is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Serves as a starting material for creating complex chelating agents and catalysts in metal-organic chemistry.
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological systems.
• Custom Synthesis: A critical substrate for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	1-Chloroisoquinoline-4-Carboxylic Acid
CAS No.	1260794-26-0
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	4-Carboxy-1-chloroisoquinoline; 1-Chloro-4-isoquinolinecarboxylic Acid; 1-Chloroisoquinoline-4-carboxylic acid; Isoquinoline-4-carboxylic acid, 1-chloro-; 1260794-26-0
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.