Description

5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine is a versatile and high-value brominated tetrahydroisoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its functionalized amine and bromine groups, which enable precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, including central nervous system (CNS) agents, kinase inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce the tetrahydroisoquinoline scaffold.
• Chemical Biology & Proteomics: Serves as a valuable scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Research: Investigated as a monomer or functional unit for creating novel organic electronic materials or polymers.

Basic Information

Product Name	5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine
CAS No.	1260779-54-1
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	8-Amino-5-bromo-1,2,3,4-tetrahydroisoquinoline; 5-Bromo-8-amino-1,2,3,4-tetrahydroisoquinoline; 5-Bromo-1,2,3,4-tetrahydro-8-isoquinolinamine; 5-Bromo-THIQ-8-amine; 1260779-54-1; 5-Br-THIQ-8-NH2
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment. For long-term storage, consider keeping the material under an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.