Description

2-Boc-5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine is a high-purity, protected amine building block of significant value in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular construction, particularly in the development of complex pharmacologically active molecules. It is primarily utilized by the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Chemistry: Used to incorporate the tetrahydroisoquinoline scaffold into peptide analogs to enhance stability and biological activity.
• Library Synthesis: Employed in combinatorial and parallel synthesis for the rapid generation of diverse compound libraries for high-throughput screening.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Chemical Biology: Useful as a probe or linker in bioconjugation and target identification studies.

Basic Information

Product Name	2-Boc-5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine
CAS No.	1260763-55-0
Molecular Formula	C14H19BrN2O2
Molecular Weight	327.22 g/mol
Synonyms	8-Amino-5-bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; tert-Butyl 8-amino-5-bromo-3,4-dihydro-1H-isoquinoline-2(2H)-carboxylate; 5-Bromo-8-amino-1,2,3,4-tetrahydroisoquinoline-2-N-Boc; 2-(tert-Butoxycarbonyl)-5-bromo-1,2,3,4-tetrahydroisoquinolin-8-amine; Boc-5-Br-THIQ-8-NH2; 1260763-55-0
EINECS	Contact for details

Quality Control

Our 2-Boc-5-Bromo-1,2,3,4-Tetrahydroisoquinolin-8-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.