Description

n-Boc-3-(Hydroxymethyl)-7-Methoxyindole is a protected indole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a Boc-protected amine and a hydroxymethyl group, which provides orthogonal reactivity for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Synthesis: Used in the construction of non-natural amino acids and peptide-like structures for medicinal chemistry.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags, enzyme inhibitors, and other molecular probes for biological research.
• Academic & Contract Research: Essential reagent for methodology development and complex natural product synthesis in academic and CRO laboratories.

Basic Information

Product Name	n-Boc-3-(Hydroxymethyl)-7-Methoxyindole
CAS No.	1260683-23-5
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-Boc-3-(hydroxymethyl)-7-methoxyindole; tert-Butyl 3-(hydroxymethyl)-7-methoxy-1H-indole-1-carboxylate; 7-Methoxy-1H-indole-3-methanol, 1-(1,1-dimethylethyl) ester; 1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)-7-methoxyindole; Boc-3-(CH2OH)-7-OMe-Indole; 3-Hydroxymethyl-7-methoxyindole N-Boc protected; N-Boc-7-methoxyindole-3-methanol
EINECS	Contact for details

Quality Control

Our n-Boc-3-(Hydroxymethyl)-7-Methoxyindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.