Description

7-Bromo-3,3-dimethylindoline is a halogenated indoline derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core structure is prized for enabling the construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromine functionality and a constrained indoline scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor modulators, and other bioactive heterocycles.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, where the bromine atom allows for further functionalization to optimize biological activity.
• Material Science Precursor: Serves as a monomer or starting material for the synthesis of organic semiconductors, dyes, and photoactive compounds.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to create more complex molecular architectures.
• Ligand and Catalyst Development: Useful framework for constructing novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	7-Bromo-3,3-dimethylindoline
CAS No.	1260675-93-1
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	7-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole; 3,3-Dimethyl-7-bromoindoline; 1H-Indole, 7-bromo-2,3-dihydro-3,3-dimethyl-; 7-Bromo-3,3-dimethylindoline; 7-Bromo-3,3-dimethyl-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our 7-Bromo-3,3-dimethylindoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.