Description

6-Trifluoromethoxy-1H-Benzoimidazole-2-Carbaldehyde is a high-value, multifunctional heterocyclic building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive aldehyde group and the electron-withdrawing trifluoromethoxy substituent. It is primarily sought after by the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in developing next-generation fungicides and herbicides where the benzimidazole core and fluorine atoms enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and proteomics research.
• Custom Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	6-Trifluoromethoxy-1H-Benzoimidazole-2-Carbaldehyde
CAS No.	1260675-84-0
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	6-(Trifluoromethoxy)-1H-benzimidazole-2-carboxaldehyde; 6-(Trifluoromethoxy)-1H-benzo[d]imidazole-2-carbaldehyde; 1H-Benzimidazole-2-carboxaldehyde, 6-(trifluoromethoxy)-; 2-Formyl-6-trifluoromethoxybenzimidazole; 6-Trifluoromethoxy-2-formylbenzimidazole; 6-Trifluoromethoxybenzimidazole-2-carbaldehyde; 6-Trifluoromethoxy-1H-benzoimidazole-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethoxy-1H-Benzoimidazole-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.