Description

(5-Phenyl-Pyrrolidin-3-Yl)-Methanol is a versatile pyrrolidine-based chiral building block and intermediate of significant interest in advanced organic synthesis. Its structure, featuring both a phenyl-substituted pyrrolidine ring and a hydroxymethyl group, makes it a valuable scaffold for constructing complex molecules with potential biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	(5-Phenyl-Pyrrolidin-3-Yl)-Methanol
CAS No.	1260671-14-4
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	3-(Hydroxymethyl)-5-phenylpyrrolidine; 5-Phenyl-3-pyrrolidinemethanol; (5-Phenyl-3-pyrrolidinyl)methanol; 3-Pyrrolidinemethanol, 5-phenyl-; (3R)-5-Phenylpyrrolidin-3-ylmethanol (for enantiopure forms); (3S)-5-Phenylpyrrolidin-3-ylmethanol (for enantiopure forms)
EINECS	Contact for details

Quality Control

Our (5-Phenyl-Pyrrolidin-3-Yl)-Methanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details (racemic or enantiopure grades available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.