Description

(5-(Trifluoromethyl)Thiophen-2-Yl)Methanol is a high-value fluorinated thiophene derivative, a crucial building block in modern synthetic chemistry. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile hydroxymethyl functionality, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group often improves metabolic stability, lipophilicity, and biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, creating compound libraries for screening, and developing novel catalytic processes.
• Ligand and Catalyst Design: The thiophene and alcohol moieties make it a valuable scaffold for constructing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	(5-(Trifluoromethyl)Thiophen-2-Yl)Methanol
CAS No.	1260670-71-0
Molecular Formula	C6H5F3OS
Molecular Weight	182.16 g/mol
Synonyms	2-(Hydroxymethyl)-5-(trifluoromethyl)thiophene; 5-(Trifluoromethyl)-2-thiophenemethanol; (5-Trifluoromethyl-2-thienyl)methanol; α-(Trifluoromethyl)thiophene-2-methanol; 2-Thiophenemethanol, 5-(trifluoromethyl)-; 1260670-71-0
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Each batch of (5-(Trifluoromethyl)Thiophen-2-Yl)Methanol is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.