Description

Ethyl 5-Bromo-2-((tert-Butoxycarbonyl)Amino)Thiophene-3-Carboxylate is a high-purity, protected thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex heterocyclic scaffolds, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiophene-based drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with heterocyclic cores.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and other functional materials.
• Chemical Synthesis: Versatile reagent for Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to introduce functionalized thiophene units.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	Ethyl 5-Bromo-2-((tert-Butoxycarbonyl)Amino)Thiophene-3-Carboxylate
CAS No.	1260664-49-0
Molecular Formula	C12H16BrNO4S
Molecular Weight	350.23 g/mol
Synonyms	Ethyl 5-Bromo-2-((Boc)Amino)Thiophene-3-Carboxylate; 5-Bromo-2-[(tert-butoxycarbonyl)amino]thiophene-3-carboxylic Acid Ethyl Ester; 2-((tert-Butoxycarbonyl)Amino)-5-Bromothiophene-3-Carboxylic Acid Ethyl Ester; Boc-5-Bromo-2-Aminothiophene-3-Carboxylic Acid Ethyl Ester; 1260664-49-0; tert-Butyl N-(5-Bromo-3-(ethoxycarbonyl)thiophen-2-yl)carbamate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Bromo-2-((tert-Butoxycarbonyl)Amino)Thiophene-3-Carboxylate is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.