Description

2-(4-Fluoro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, synthetically derived organic compound with the CAS registry number 1260644-08-3. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs targeting central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those with tetrahydroisoquinoline-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules in gram to kilogram scales for pre-clinical studies.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition or receptor binding activities in early-stage drug discovery.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	1260644-08-3
Molecular Formula	C17H16FNO3
Molecular Weight	301.31 g/mol
Synonyms	6-Methoxy-2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 2-(4-Fluorophenyl)-6-methoxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 1260644-08-3; 2-(4-Fluoro-phenyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid; 1,2,3,4-Tetrahydro-6-methoxy-2-(4-fluorophenyl)-1-isoquinolinecarboxylic acid; 6-Methoxy-2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.