Description

2-(4-Fluoro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydroisoquinoline scaffold and fluorine substitution. This compound is of significant value for medicinal chemistry research and development, offering a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas targeting the central nervous system and other complex biological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged tetrahydroisoquinoline core.
• Chemical Synthesis: Serves as a precursor for creating more complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and receptor binding studies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals for advanced applications.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	1260644-01-6
Molecular Formula	C16H14FNO3
Molecular Weight	287.29 g/mol
Synonyms	6-Hydroxy-2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 2-(4-Fluorophenyl)-6-hydroxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-6-hydroxy-2-(4-fluorophenyl)-1-isoquinolinecarboxylic acid; CAS 1260644-01-6; 2-(4-Fluorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 6-Hydroxy-2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 1-Carboxy-2-(4-fluorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.