Description

Ethyl 2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new isoquinoline-based compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the manufacture of complex APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies to investigate enzyme inhibition or receptor binding.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	Ethyl 2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260643-22-8
Molecular Formula	C18H18ClNO3
Molecular Weight	331.79 g/mol
Synonyms	Ethyl 2-(4-chlorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 1,2,3,4-Tetrahydro-6-hydroxy-2-(4-chlorophenyl)isoquinoline-1-carboxylic Acid Ethyl Ester; 6-Hydroxy-2-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester; CAS 1260643-22-8; 2-(4-Chlorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester; 1-Carbethoxy-2-(4-chlorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.