Description

5-(Trifluoromethyl)-1H-Benzo[D]Imidazole Hcl is a high-purity, halogenated benzimidazole derivative offered as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for advanced chemical synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Building block for developing new generation fungicides, herbicides, and plant growth regulators leveraging the trifluoromethyl group's metabolic stability.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel N-donor ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Biochemical Probe Synthesis: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Benzo[D]Imidazole Hcl
CAS No.	1260642-93-0
Molecular Formula	C8H6ClF3N2
Molecular Weight	234.59 g/mol
Synonyms	5-(Trifluoromethyl)-1H-benzimidazole hydrochloride; 1H-Benzimidazole, 5-(trifluoromethyl)-, hydrochloride; 5-(Trifluoromethyl)benzimidazole HCl; 5-Trifluoromethylbenzimidazole hydrochloride; 5-CF3-Benzimidazole HCl; Benzimidazole, 5-trifluoromethyl-, hydrochloride; 1260642-93-0
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-Benzo[D]Imidazole Hcl is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.