Description

1-Isoquinolinecarboxylic Acid, 6-Fluoro-1,2,3,4-Tetrahydro- is a high-purity fluorinated tetrahydroisoquinoline derivative, serving as a critical pharmaceutical intermediate and advanced building block in organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the carboxylic acid functional group, enabling precise molecular construction for complex targets. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: An essential component for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Precursor: Acts as a monomer or functional additive in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-Isoquinolinecarboxylic Acid, 6-Fluoro-1,2,3,4-Tetrahydro-
CAS No.	1260641-86-8
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 6-Fluoro-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 1-Carboxy-6-fluoro-1,2,3,4-tetrahydroisoquinoline; 6-Fluoro-THIQ-1-carboxylic acid; F-THIQ-COOH; 6-Fluoro-1,2,3,4-tetrahydroisoquinoline-1-carboxylate (acid form)
EINECS	Contact for details

Quality Control

Our 1-Isoquinolinecarboxylic Acid, 6-Fluoro-1,2,3,4-Tetrahydro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.