Description

2-n-Boc-7-Bromo-3,4-Dihydro-1H-Isoquinoline-2,3-Dicarboxylic Acid is a high-purity, protected heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile functional groups, which enable its use as a key intermediate in constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bromine and carboxylic acid functionalities for structural diversification.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Peptidomimetic Chemistry: The protected dihydroisoquinoline core is valuable for creating conformationally constrained peptide analogs.
• Material Science Research: Potential use as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-n-Boc-7-Bromo-3,4-Dihydro-1H-Isoquinoline-2,3-Dicarboxylic Acid
CAS No.	1260641-72-2
Molecular Formula	C₁₇H₁₈BrNO₆
Molecular Weight	412.23 g/mol
Synonyms	7-Bromo-2-[(tert-butoxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-2,3-dicarboxylic acid; 2-(tert-Butoxycarbonyl)-7-bromo-1,2,3,4-tetrahydroisoquinoline-2,3-dicarboxylic acid; 2-Boc-7-Bromo-1,2,3,4-tetrahydroisoquinoline-2,3-dicarboxylic Acid; 7-Bromo-2-N-Boc-1,2,3,4-tetrahydroisoquinoline-2,3-dicarboxylic Acid; 1260641-72-2; tert-Butyl 7-bromo-2,3-bis(carboxy)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2-n-Boc-7-Bromo-3,4-Dihydro-1H-Isoquinoline-2,3-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature, it should be stored separately from strong acids and organic solvents. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.