Description

7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is a high-purity, synthetically derived organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride
CAS No.	1260640-87-6
Molecular Formula	C10H11BrClNO2
Molecular Weight	292.56 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride; 1,2,3,4-Tetrahydro-7-bromo-1-isoquinolinecarboxylic acid hydrochloride; 7-Bromo-THIQ-1-COOH HCl; 7-Bromo-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid monohydrochloride; (7-Bromo-1,2,3,4-tetrahydroisoquinolin-1-yl)formic acid hydrochloride; 7-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to industry best practices suitable for research and development applications, with the capability to meet specific customer requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.