Description

Ethyl 2-(4-Chloro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1260640-41-2. This compound is a key synthetic building block valued for its complex heterocyclic structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of new chemical entities, particularly in therapeutic areas requiring sophisticated molecular scaffolds.

Application

This specialized intermediate serves critical functions in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and novel synthetic methodologies.

Basic Information

Product Name	Ethyl 2-(4-Chloro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260640-41-2
Molecular Formula	C19H20ClNO3
Molecular Weight	345.82 g/mol
Synonyms	Ethyl 2-(4-chlorophenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 1,2,3,4-Tetrahydro-2-(4-chlorophenyl)-6-methoxyisoquinoline-1-carboxylic acid ethyl ester; 2-(4-Chlorophenyl)-6-methoxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid ethyl ester; 1260640-41-2; UNII-7K6N2W0H4I; 7K6N2W0H4I; SCHEMBL21806627; DTXSID60664669
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chloro-Phenyl)-6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.