Description

Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound matters as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value organic molecules for research and development purposes.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260639-89-1
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	Ethyl 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylate; 1-Carbethoxy-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline; 6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid Ethyl Ester; 1,2,3,4-Tetrahydro-6-Methoxyisoquinoline-1-Carboxylic Acid Ethyl Ester; ETIQ-1-COOEt; CAS 1260639-89-1
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.