Description

7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including potential central nervous system (CNS) drugs and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialized fine chemicals and complex organic molecules requiring the tetrahydroisoquinoline core structure.
• Academic & Industrial R&D: Employed in universities and corporate R&D labs for exploratory synthesis and the development of new synthetic methodologies.

Basic Information

Product Name	7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	1260639-77-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	1,2,3,4-Tetrahydro-7-methylisoquinoline-1-carboxylic acid; 7-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 7-Methyl-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 7-Methyl-THIQ-1-COOH; (1S)-7-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (for chiral form); 7-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.