Description

Ethyl 6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-value, synthetically versatile organic compound belonging to the tetrahydroisoquinoline class. It serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the construction of complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks and introducing the tetrahydroisoquinoline pharmacophore into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Fine Chemical Production: Serves as a starting material or intermediate in the multi-step synthesis of specialty chemicals and advanced materials.
• Academic & Industrial R&D: Utilized in chemical research for developing new synthetic methodologies and exploring novel chemical entities.

Basic Information

Product Name	Ethyl 6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260638-15-0
Molecular Formula	C12H14ClNO2
Molecular Weight	239.70 g/mol
Synonyms	Ethyl 6-Chloro-3,4-dihydro-1H-isoquinoline-1-carboxylate; 6-Chloro-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester; 1-Carbethoxy-6-chloro-1,2,3,4-tetrahydroisoquinoline; Ethyl 6-Chloro-1,2,3,4-tetrahydro-1-isoquinolinecarboxylate; 6-Chloro-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.