Description

Ethyl 2-(4-Chloro-Phenyl)-6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound serves as a critical building block in the synthesis of complex molecules, offering a strategic advantage for process chemists. It is primarily utilized by pharmaceutical and biotechnology companies focused on developing new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of complex heterocyclic frameworks due to its functionalized tetrahydroisoquinoline core.
• Process Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry and method development.

Basic Information

Product Name	Ethyl 2-(4-Chloro-Phenyl)-6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260638-02-5
Molecular Formula	C18H17BrClNO2
Molecular Weight	394.69 g/mol
Synonyms	Ethyl 2-(4-chlorophenyl)-6-bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 6-Bromo-2-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid ethyl ester; 1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid, 6-bromo-2-(4-chlorophenyl)-, ethyl ester; 1260638-02-5; Ethyl 6-bromo-2-(4-chlorophenyl)-1,2,3,4-tetrahydro-1-isoquinolinecarboxylate; 2-(4-Chlorophenyl)-6-bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chloro-Phenyl)-6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.