Description

Ethyl 2-(4-Chloro-Phenyl)-6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a key scaffold for developing new-generation pesticides and herbicides with specific modes of action.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic molecules due to its reactive functional groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of specialty chemicals.

Basic Information

Item	Details
Product Name	Ethyl 2-(4-Chloro-Phenyl)-6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate
CAS No.	1260637-93-1
Molecular Formula	C18H17Cl2NO2
Molecular Weight	350.24 g/mol
Synonyms	Ethyl 2-(4-chlorophenyl)-6-chloro-1,2,3,4-tetrahydroisoquinoline-1-carboxylate; 1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid, 2-(4-chlorophenyl)-6-chloro-, ethyl ester; 1260637-93-1; 2-(4-Chlorophenyl)-6-chloro-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic Acid Ethyl Ester; 6-Chloro-2-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chloro-Phenyl)-6-Chloro-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to ensure product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.