Description

2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas such as central nervous system (CNS) and cardiovascular research.

Application

This compound serves as a key building block in various high-value chemical syntheses. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds for academic and industrial research.

Basic Information

Product Name	2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	1260637-90-8
Molecular Formula	C₁₆H₁₄ClNO₃
Molecular Weight	303.74 g/mol
Synonyms	6-Hydroxy-2-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 2-(4-Chlorophenyl)-6-hydroxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-6-hydroxy-2-(4-chlorophenyl)-1-isoquinolinecarboxylic acid; 1260637-90-8; 2-(p-Chlorophenyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Phenyl)-6-Hydroxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary packaging or amber glass. For long-term storage, consider maintaining the material under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.