Description

7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1260637-81-7. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Synthesis Building Block: Used for constructing complex heterocyclic frameworks and introducing the tetrahydroisoquinoline moiety into target molecules.
• Agrochemical Research: Serves as a starting material for developing new pesticides and herbicides with specific biological activity.
• Chemical Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing.
• Academic & R&D: Utilized in university and corporate research settings for studying chemical reactions and developing new synthetic methodologies.
• Fine Chemical Production: Integrated into the manufacturing process of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride
CAS No.	1260637-81-7
Molecular Formula	C12H15NO2 • HCl
Molecular Weight	241.71 g/mol (Free base: 205.25 g/mol)
Synonyms	1-Carboxy-7-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 7-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid HCl; 7-Methyl-THIQ-1-COOH hydrochloride; 1,2,3,4-Tetrahydro-7-methylisoquinoline-1-carboxylic acid hydrochloride; 7-Methyl-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid monohydrochloride
EINECS	Contact for details

Quality Control

Our 7-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.