Description

6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those with isoquinoline or tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a starting material or intermediate for the preparation of more complex heterocyclic compounds and fine chemicals.
• Academic Research: Employed in university and institutional labs for methodological development and the study of novel organic reactions.
• Library Synthesis: Valuable for creating diverse compound libraries for high-throughput screening in biological assays.
• Neuroscience Drug Development: Particularly relevant for projects targeting receptors and enzymes where the bromo-substituted tetrahydroisoquinoline moiety is pharmacologically active.

Basic Information

Product Name	6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride
CAS No.	1260637-73-7
Molecular Formula	C10H11BrClNO2
Molecular Weight	292.56 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride; 1,2,3,4-Tetrahydro-6-bromo-1-isoquinolinecarboxylic acid hydrochloride; 6-Bromo-THIQ-1-COOH HCl; 6-Bromo-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid hydrochloride; 6-Bromotetrahydroisoquinoline-1-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.