Description

Ethyl 6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride is a high-purity, synthetically valuable organic building block. This compound is critical for pharmaceutical research and development, serving as a key intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Chemical Synthesis Building Block: The bromo and ester functional groups make it a versatile scaffold for further functionalization via cross-coupling reactions and nucleophilic substitutions.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and organic synthesis.
• Process Chemistry: Serves as a starting material for scaling up the production of target compounds under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	Ethyl 6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride
CAS No.	1260637-67-9
Molecular Formula	C₁₂H₁₄BrNO₂·HCl
Molecular Weight	320.61 g/mol (Free base: 284.15 g/mol)
Synonyms	6-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid ethyl ester hydrochloride; Ethyl 6-bromo-3,4-dihydro-1H-isoquinoline-1-carboxylate hydrochloride; 1-Carbethoxy-6-bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6-Bromo-THIQ-1-COOEt HCl; 1260637-67-9; 6-Bromo-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic Acid Ethyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.