Description

6-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class, serving as a critical advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. Its value lies in its unique fused-ring structure, which is integral to the development of active pharmaceutical ingredients (APIs) and other fine chemicals. This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex nitrogen-containing heterocycles in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex ligands for catalysts.
• Biochemical Research: Potential use as a scaffold or inhibitor in biochemical and pharmacological studies.

Basic Information

Item	Detail
Product Name	6-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid
CAS No.	1260637-29-3
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	6-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid; 1,2,3,4-Tetrahydro-6-methyl-1-isoquinolinecarboxylic acid; 6-Methyl-THIQ-1-COOH; 6-Methyl-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid; (1S)-6-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (for chiral form); 6-Methyl-1-carboxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.