Description

6-Methoxy-5-Nitro-7-Azaindole is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Process Chemistry: Serves as a starting material or intermediate in scalable API manufacturing processes.
• Organic Synthesis: A versatile azaindole derivative for constructing complex heterocyclic frameworks in academic and industrial R&D.
• Biochemical Research: Potential use in developing chemical probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	6-Methoxy-5-Nitro-7-Azaindole
CAS No.	1260386-18-2
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	5-Nitro-6-methoxy-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 6-methoxy-5-nitro-; 6-Methoxy-5-nitro-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 6-methoxy-5-nitro-; 5-Nitro-6-methoxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-Nitro-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.