Description

Minoxidil-D10 is a deuterated analog of the well-known pharmaceutical agent minoxidil, specifically designed for use as an internal standard in analytical chemistry. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and bioequivalence studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities that require precise measurement of minoxidil in complex biological matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of minoxidil in biological fluids (plasma, serum, urine).
• Quantitative reference material in pharmaceutical research and development for drug metabolism and pharmacokinetics (DMPK) studies.
• Critical component in bioanalytical method development and validation for generic and innovative drug formulations.
• Use in clinical trial sample analysis to ensure data integrity and regulatory compliance.
• Calibration and quality control in forensic and toxicological analysis.
• Stable isotope dilution assay for accurate quantification in complex sample matrices.

Basic Information

Product Name	Minoxidil-D10
CAS No.	1260373-92-9
Molecular Formula	C9H5D10N5O
Molecular Weight	215.30 g/mol
Synonyms	6-(1-Piperidinyl)-2,4-pyrimidinediamine-d10 3-oxide; 2,4-Diamino-6-piperidino-d10-pyrimidine 3-oxide; Minoxidil Deuterated (D10); Minoxidil-d10; [d10]-Minoxidil; LONITEN-d10; Deuterated Minoxidil Internal Standard; Minoxidil (hexadeuterio(piperidino-2,3,4,5,6-d5)).
EINECS	Contact for details

Quality Control

Our Minoxidil-D10 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced spectroscopic and chromatographic tests, including NMR, HPLC, and MS. We ensure compliance with relevant standards for high-purity reference materials, supporting your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.