Description

Methyl 5-(Benzyloxy)-3-Chlorobenzo[B]Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzothiophene core structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzothiophene-based drug candidates for therapeutic applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct more elaborate heterocyclic systems.
• API Development: Serves as a critical raw material in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating new chemical reactions and heterocyclic chemistry.

Basic Information

Product Name	Methyl 5-(Benzyloxy)-3-Chlorobenzo[B]Thiophene-2-Carboxylate
CAS No.	1259977-93-9
Molecular Formula	C17H13ClO3S
Molecular Weight	332.80 g/mol
Synonyms	Methyl 5-(benzyloxy)-3-chlorobenzo[b]thiophene-2-carboxylate; 3-Chloro-5-(benzyloxy)benzo[b]thiophene-2-carboxylic acid methyl ester; 5-Benzyloxy-3-chlorobenzo[b]thiophene-2-carboxylic acid methyl ester; Methyl 3-chloro-5-(phenylmethoxy)-1-benzothiophene-2-carboxylate; Benzo[b]thiophene-2-carboxylic acid, 3-chloro-5-(phenylmethoxy)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(Benzyloxy)-3-Chlorobenzo[B]Thiophene-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.