Description

7-Chloro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1259326-51-6. This compound is a critical building block in the synthesis of complex organic molecules, valued for its defined isoquinoline scaffold and reactive nitro and chloro substituents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex heterocyclic compounds and alkaloid analogs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in laboratory settings.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Academic & Industrial R&D: Used in universities and corporate R&D labs for exploratory chemistry and process development.

Basic Information

Product Name	7-Chloro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1259326-51-6
Molecular Formula	C9H10ClN2O2·HCl
Molecular Weight	263.56 g/mol
Synonyms	7-Chloro-6-nitro-1,2,3,4-tetrahydroisoquinoline HCl; 7-Chloro-6-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-chloro-6-nitroisoquinoline hydrochloride; 7-Chloro-6-nitro-3,4-dihydro-1H-isoquinoline hydrochloride; 7-Chloro-6-nitro-1,2,3,4-tetrahydroisoquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 7-Chloro-6-Nitro-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.