Description

Thieno[2,3-C]Pyridine-2-Carboxylic Acid, 4,5,6,7-Tetrahydro-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate (API) characterized by its fused heterocyclic structure. This compound is of significant commercial importance as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel therapeutic agents, especially for neurological and psychiatric conditions.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for the construction of complex polycyclic frameworks due to its reactive ester functionality and constrained bicyclic system.
• Research & Development (R&D): Employed in academic and industrial laboratories for method development, structure-activity relationship (SAR) studies, and exploratory synthesis.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for candidate drugs during clinical development phases.
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents with specific biological activity.
• Material Science Precursor: Investigated for the synthesis of specialized organic ligands and functional materials.

Basic Information

Product Name	Thieno[2,3-C]Pyridine-2-Carboxylic Acid, 4,5,6,7-Tetrahydro-, Methyl Ester
CAS No.	1259287-72-3
Molecular Formula	C10H11NO2S
Molecular Weight	209.26 g/mol
Synonyms	Methyl 4,5,6,7-tetrahydrothieno[2,3-c]pyridine-2-carboxylate; 4,5,6,7-Tetrahydrothieno[2,3-c]pyridine-2-carboxylic acid methyl ester; Thieno[2,3-c]pyridine-2-carboxylic acid, 4,5,6,7-tetrahydro-, methyl ester; Methyl tetrahydrothienopyridine-2-carboxylate; Tetrahydrothieno[2,3-c]pyridine-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Thieno[2,3-C]Pyridine-2-Carboxylic Acid, 4,5,6,7-Tetrahydro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for demanding pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.