Description

1,3-Dichloro-5-Fluoroisoquinoline is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique halogenated isoquinoline scaffold. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a building block for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing diverse functional groups.
• Academic & Contract Research: Essential for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1,3-Dichloro-5-Fluoroisoquinoline
CAS No.	1259223-98-7
Molecular Formula	C9H4Cl2FN
Molecular Weight	216.04 g/mol
Synonyms	5-Fluoro-1,3-dichloroisoquinoline; 1,3-Dichloro-5-fluoro-isoquinoline; Isoquinoline, 1,3-dichloro-5-fluoro-; 1259223-98-7
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-5-Fluoroisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GLP (Good Laboratory Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.