Description

3-Indolizinecarboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and R&D laboratories focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a building block for synthesizing new herbicides, fungicides, and insecticides with potential novel modes of action.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated indolizine core.
• Academic & Contract Research: A critical reagent for methodological studies and the exploration of new heterocyclic chemistry in university and CRO settings.
• Peptidomimetics: The carboxylic acid functionality allows for incorporation into peptide backbones to create novel bioisosteres and enzyme inhibitors.

Basic Information

Product Name	3-Indolizinecarboxylic Acid
CAS No.	1259060-82-6
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	1H-Indolizine-3-carboxylic acid; Indolizine-3-carboxylic acid; 3-Carboxyindolizine; 1-Azaindole-3-carboxylic acid (related structural isomer); Pyrrolo[1,2-a]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Indolizinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.