Description

tert-Butyl (5-Iodothiazol-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct iodothiazole core. This compound is of significant value in modern medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Heterocyclic Compound Synthesis: Serves as a critical scaffold for constructing complex thiazole-containing heterocycles with potential biological activity.
• Agrochemical Development: Employed in the research and development of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and APIs under cGMP conditions.

Basic Information

Product Name	tert-Butyl (5-Iodothiazol-4-Yl)Carbamate
CAS No.	1258934-68-7
Molecular Formula	C8H11IN2O2S
Molecular Weight	326.15 g/mol
Synonyms	Boc-5-Iodo-4-aminothiazole; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-iodo-2-thiazole; 5-Iodo-4-((tert-butoxycarbonyl)amino)thiazole; tert-Butyl N-(5-iodo-1,3-thiazol-4-yl)carbamate; 4-Amino-5-iodothiazole, N-Boc protected; 5-Iodo-4-aminothiazole Boc derivative; (5-Iodothiazol-4-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Iodothiazol-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.