Description

Ethyl 2-(4-Chlorophenylamino)-4,9-Dioxo-4,9-Dihydronaphtho[2,3-B]Thiophen-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the naphthothiophene class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in the development of novel therapeutic and crop protection agents. The compound, with CAS number 1258638-44-6, offers a critical structural motif for creating molecules with targeted biological activity.

Application

This specialized intermediate serves as a crucial precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Light-Emitting Diode (OLED) Materials Research: Serves as a potential electron-transport or host material in the development of next-generation display technologies due to its fused aromatic system.
• Dye and Pigment Intermediate: Acts as a precursor for synthesizing specialized organic dyes and pigments with specific colorfastness and stability properties.
• Academic and R&D Laboratories: Utilized in synthetic organic chemistry research to explore new reactions and construct complex molecular architectures.
• Material Science: Investigated for use in organic semiconductors and other functional materials requiring specific electronic properties.

Basic Information

Item	Detail
Product Name	Ethyl 2-(4-Chlorophenylamino)-4,9-Dioxo-4,9-Dihydronaphtho[2,3-B]Thiophen-3-Carboxylate
CAS No.	1258638-44-6
Molecular Formula	C21H14ClNO4S
Molecular Weight	411.86 g/mol
Synonyms	Ethyl 2-[(4-chlorophenyl)amino]-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylate; 2-[(4-Chlorophenyl)amino]-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid ethyl ester; Naphtho[2,3-b]thiophene-3-carboxylic acid, 2-[(4-chlorophenyl)amino]-4,9-dihydro-4,9-dioxo-, ethyl ester; CAS 1258638-44-6; 4,9-Dihydro-4,9-dioxonaphtho[2,3-b]thiophene-2-amine, N-(4-chlorophenyl)-3-(ethoxycarbonyl)-; Ethyl 2-(p-chloroanilino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Chlorophenylamino)-4,9-Dioxo-4,9-Dihydronaphtho[2,3-B]Thiophen-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.