Description

4-Methyl-3-(Pyridine-2-Sulfonyl)-Thiophene-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyridine and thiophene moieties. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a versatile scaffold for developing new generation pesticides and herbicides with improved efficacy.
• Material Science: Used in the research and development of organic electronic materials and functional polymers due to its electron-rich structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-Methyl-3-(Pyridine-2-Sulfonyl)-Thiophene-2-Carbaldehyde
CAS No.	1258283-07-6
Molecular Formula	C12H9NO3S2
Molecular Weight	279.33 g/mol
Synonyms	4-Methyl-3-(pyridin-2-ylsulfonyl)thiophene-2-carbaldehyde; 3-[(Pyridin-2-yl)sulfonyl]-4-methylthiophene-2-carboxaldehyde; 2-Thiophenecarboxaldehyde, 4-methyl-3-(2-pyridinylsulfonyl)-; 4-Methyl-3-(2-pyridylsulfonyl)thiophene-2-carbaldehyde; 1258283-07-6; 4-Methyl-3-(pyridine-2-sulfonyl)thiophene-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(Pyridine-2-Sulfonyl)-Thiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.