Description

4-Bromo-2-Methyl-7-Nitro-2,3-Dihydro-Isoindol-1-One is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for advanced research and development in pharmaceutical chemistry, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or oncological pathways.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Potential use in the synthesis of organic semiconductors, dyes, or photoactive materials due to its nitro and bromo functional groups.
• Chemical Biology: Used as a molecular probe or a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects requiring specialized heterocycles.

Basic Information

Product Name	4-Bromo-2-Methyl-7-Nitro-2,3-Dihydro-Isoindol-1-One
CAS No.	1257996-66-9
Molecular Formula	C9H7BrN2O3
Molecular Weight	271.07 g/mol
Synonyms	4-Bromo-2-methyl-7-nitro-2,3-dihydro-1H-isoindol-1-one; 1H-Isoindol-1-one, 4-bromo-2,3-dihydro-2-methyl-7-nitro-; 4-Bromo-2-methyl-7-nitroisoindolin-1-one; 2,3-Dihydro-2-methyl-7-nitro-4-bromo-1H-isoindol-1-one; 7-Nitro-4-bromo-2-methylisoindolin-1-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-7-Nitro-2,3-Dihydro-Isoindol-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.