Description

3-Bromo-5-Iodophenylboronic Acid is a high-value, multi-halogenated boronic acid derivative that serves as a versatile building block in modern synthetic chemistry. Its primary importance lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-purity intermediate for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex halogenated biphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogen substitution patterns for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology & Proteomics: Utilized as a building block for synthesizing molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & Industrial R&D: A critical reagent for methodological development in cross-coupling chemistry and the exploration of new chemical space in discovery libraries.

Basic Information

Product Name	3-Bromo-5-Iodophenylboronic Acid
CAS No.	1257793-09-1
Molecular Formula	C6H5BBrIO2
Molecular Weight	326.82 g/mol
Synonyms	(3-Bromo-5-iodophenyl)boronic acid; 3-Bromo-5-iodobenzeneboronic acid; B-(3-Bromo-5-iodophenyl)boronic acid; 3-Br-5-I-C6H3B(OH)2; 3-Bromo-5-iodophenyl-B(OH)2; Boronic acid, B-(3-bromo-5-iodophenyl)-; 1257793-09-1
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Iodophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.