Description

1-Boc-5-Bromo-4-Methyl-1H-Indazole is a high-purity, advanced pharmaceutical intermediate featuring a protected indazole core. This compound is essential for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other oncology therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-Boc-5-Bromo-4-Methyl-1H-Indazole
CAS No.	1257535-48-0
Molecular Formula	C₁₃H₁₅BrN₂O₂
Molecular Weight	311.18 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-5-bromo-4-methyl-1H-indazole; 5-Bromo-4-methyl-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-bromo-4-methyl-1H-indazole-1-carboxylate; 1-Boc-5-bromo-4-methylindazole; Boc-5-Br-4-Me-indazole; 5-Bromo-4-methyl-1-(tert-butoxycarbonyl)indazole; 1H-Indazole-1-carboxylic acid, 5-bromo-4-methyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of 1-Boc-5-Bromo-4-Methyl-1H-Indazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for advanced R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.