Description

1H-Indazole, 7-Bromo-6-Methyl- CAS NO 1257535-45-7 is a high-purity, advanced pharmaceutical intermediate belonging to the indazole class of heterocyclic compounds. This specialized brominated derivative is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex molecular architectures due to its reactive bromo substituent.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development in pharmacokinetic and metabolic studies.

Basic Information

Product Name	1H-Indazole, 7-Bromo-6-Methyl-
CAS No.	1257535-45-7
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	7-Bromo-6-methyl-1H-indazole; 6-Methyl-7-bromoindazole; 7-Bromo-6-methylindazole; 1H-Indazole, 7-bromo-6-methyl-; 1257535-45-7; 7-Bromo-6-methyl-1H-indazole; 6-Methyl-7-bromo-1H-indazole
EINECS	Contact for details

Quality Control

Our production of 1H-Indazole, 7-Bromo-6-Methyl- adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.