Description

1-Methyl-5-Trifluoromethyl-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the indole scaffold and the trifluoromethyl group, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioavailability and stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and specialty polymers.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its distinctive structural motif.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	1-Methyl-5-Trifluoromethyl-1H-Indole-2-Carboxylic Acid
CAS No.	1257092-36-6
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	5-(Trifluoromethyl)-1-methyl-1H-indole-2-carboxylic acid; 1-Methyl-5-(trifluoromethyl)indole-2-carboxylic acid; 2-Carboxy-1-methyl-5-trifluoromethylindole; 1-Methyl-5-trifluoromethylindole-2-carboxylic acid; MFCD30533366
EINECS	Contact for details

Quality Control

Every batch of 1-Methyl-5-Trifluoromethyl-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.