Description

Piperidine-3-thiol hydrochloride is a versatile heterocyclic building block and key intermediate in organic synthesis. Its unique structure, featuring both a piperidine ring and a thiol group, makes it a valuable precursor for the development of novel pharmaceuticals and agrochemicals. This compound is particularly sought after by research chemists and process development scientists in the pharmaceutical industry for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in the development of central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, where the piperidine-thiol moiety can impart specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation studies.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new synthetic methodologies and constructing diverse heterocyclic libraries.
• Peptidomimetics: Useful in the design and synthesis of peptidomimetic compounds, where it can mimic natural amino acid structures.

Basic Information

Product Name	Piperidine-3-thiol Hydrochloride
CAS No.	1257081-01-8
Molecular Formula	C5H12ClNS
Molecular Weight	153.67 g/mol
Synonyms	3-Mercopiperidine hydrochloride; 3-Piperidinethiol hydrochloride; Piperidine-3-thiol HCl; 1-Azabicyclo[3.3.0]octane-3-thiol hydrochloride (related bicyclic form); 3-Thiolpiperidine hydrochloride; 3-Piperidyl mercaptan hydrochloride; Hexahydro-3-pyridinethiol hydrochloride
EINECS	Contact for details

Quality Control

Our Piperidine-3-thiol hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.