Description

3-Chloro-6,7-Dihydro-5H-Isoquinolin-8-One is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique isoquinolinone scaffold, functionalized with a chlorine atom, makes it an invaluable intermediate for pharmaceutical research and fine chemical manufacturing. This compound is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and the development of novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile chemical reactivity.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides.
• Organic Light-Emitting Diode (OLED) Materials: Potential building block for electron-transport or host materials in electronic applications.
• Ligand Synthesis for Catalysis: Can be utilized to create novel nitrogen-containing ligands for transition metal catalysts.
• Academic & Industrial R&D: Employed in exploratory chemistry for constructing complex heterocyclic frameworks.

Basic Information

Product Name	3-Chloro-6,7-Dihydro-5H-Isoquinolin-8-One
CAS No.	1256821-77-8
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydroisoquinolin-8-one; 8-Isoquinolinone, 3-chloro-6,7-dihydro-5H-; 3-Chloro-6,7-dihydro-8(5H)-isoquinolinone; 3-Chloro-5,6,7,8-tetrahydro-8-isoquinolinone; 3-Chloro-8-oxo-5,6,7,8-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 3-Chloro-6,7-Dihydro-5H-Isoquinolin-8-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.