Description

5-Bromo-3-Isopropyl-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Serves as a building block for novel pesticides and herbicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule construction.
• Academic Research: Used in university and institutional labs for heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	5-Bromo-3-Isopropyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1256819-54-1
Molecular Formula	C10H11BrN2
Molecular Weight	239.11 g/mol
Synonyms	5-Bromo-3-(propan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 3-Isopropyl-5-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-(1-methylethyl)-; 5-Bromo-3-isopropyl-1H-pyrrolo[2,3-b]pyridine; 1256819-54-1; 5-Br-3-iPr-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Isopropyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.