Description

5-Bromo-3-Chloroisoquinoline is a high-value halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both bromo and chloro substituents, makes it an indispensable intermediate for constructing complex heterocyclic frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex functionalities.
• Ligand & Catalyst Development: Utilized in the design of novel chelating ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Bromo-3-Chloroisoquinoline
CAS No.	1256787-17-3
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	3-Chloro-5-bromoisoquinoline; 5-Bromo-3-chloro-isoquinoline; Isoquinoline, 5-bromo-3-chloro-; 1256787-17-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloroisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.