Description

9-Ethynyl-6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is a sophisticated heterocyclic organic compound designed for advanced research and development. This molecule is of significant interest as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block in medicinal chemistry. It is primarily utilized by pharmaceutical R&D organizations and contract research and manufacturing services (CRAMS) companies engaged in the discovery of novel therapeutic agents.

Application

This high-value chemical intermediate serves critical functions in specialized chemical synthesis:

• Pharmaceutical Intermediate: Serves as a core scaffold or precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and targeted therapies.
• Kinase Inhibitor Research: Used in the discovery and development of protein kinase inhibitors due to its complex heterocyclic structure which can interact with ATP-binding sites.
• Chemical Biology Probe: Acts as a tool compound for studying specific biological pathways and target validation in academic and industrial research settings.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale synthesis for new chemical entities (NCEs).
• Custom Synthesis Building Block: Provided to clients for further functionalization and incorporation into proprietary compound libraries.

Basic Information

Product Name	9-Ethynyl-6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile
CAS No.	1256580-24-1
Molecular Formula	C30H30N4O2
Molecular Weight	478.59 g/mol
Synonyms	9-Ethynyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-5H-benzo[b]carbazole-3-carbonitrile-11(6H)-one; UNII-6T0I6VQ9QK; 6,11-Dihydro-9-ethynyl-6,6-dimethyl-8-(4-morpholinyl-1-piperidinyl)-5H-benzo[b]carbazole-3-carbonitrile-11-one; 5H-Benzo[b]carbazole-3-carbonitrile, 6,11-dihydro-9-ethynyl-6,6-dimethyl-8-(4-morpholinyl-1-piperidinyl)-11-oxo-; 1256580-24-1; 9-Ethynyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile-11-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.