Description

9-Bromo-6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is a sophisticated, high-purity organic intermediate designed for advanced pharmaceutical research and development. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily targeted at medicinal chemists and process development scientists within the pharmaceutical and biotechnology industries, where it enables the exploration of new chemical entities and the optimization of lead compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors due to its carbazole and morpholinopiperidine motifs.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological targets and cellular processes.
• Process Chemistry: Employed in route scouting and scale-up studies for the efficient manufacturing of complex drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	9-Bromo-6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile
CAS No.	1256579-62-0
Molecular Formula	C28H29BrN4O2
Molecular Weight	533.47 g/mol
Synonyms	9-Bromo-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; 9-Bromo-6,6-dimethyl-8-(4-morpholin-1-ylpiperidin-1-yl)-5H-benzo[b]carbazole-3-carbonitrile-11(6H)-one; Benzo[b]carbazole-3-carbonitrile, 9-bromo-6,11-dihydro-6,6-dimethyl-8-(4-morpholinyl-1-piperidinyl)-11-oxo-; 1256579-62-0; BDBM50164957; AKOS025247193; ZINC000257830587; CHEMBL3186662
EINECS	Contact for details

Quality Control

Our 9-Bromo-6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.